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Tuberculosis during early antiretroviral-induced immune reconstitution in HIV-infected children.

ART drugs, leading to subtherapeutic serum levels and the development of antiretroviral drug resistance.

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Application site disorders reported in more than 1% of patients have included burning, hypopigmentation, rash, sensitivity, soreness, stinging, and tenderness.

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Chronic lung disease might predispose persons to development of acute pneumonia; in one study, the incidence of acute lower respiratory tract infection in HIV-infected children with chronic lymphoid interstitial pneumonitis was approximately 10-fold higher than in a community-based study of HIV-uninfected children ( 53).

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Although fetal infection can be cured by treating the mother, treatment failure is much higher in the presence of fetal hepatomegaly, ascites, hydrops, polyhydramnios, and placental thickening, which are signs of fetal syphilis detected on ultrasonography.

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If the lesions are larger or more extensive and not causing the patient symptoms, we may elect to follow these lesions and not remove them automatically.

Patients who develop IRIS related to cryptococcosis are more likely than those who do not develop cyrptococcal IRIS to be severely immunocompromised with disseminated infection and to have initiated potent antiretroviral therapy soon after diagnosis of cryptococcal disease ( 370); in antiretroviral-naïve patients newly diagnosed with cryptococcal meningitis, delay in potent antiretroviral therapy may be prudent until the end of the first 2 weeks of induction therapy ( CIII).

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All patients who have syphilis should be tested for HIV.

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BCG vaccine, which is not routinely administered in the United States and should not be administered to HIV-infected infants and children, has potential to cause disseminated disease (EII) ().

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Interferons, both natural or recombinant, have been used for the treatment of genital warts.

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